What are the benefits of Best Pterostilbene Supplement



What is Pterostilbene?

Pterostilbene is an antioxidant found in many plants, including almonds, grape leaves and vines, blueberries and related Vaccinium berries, peanuts, dracaena plants, and Indian kino. Blueberries are the richest dietary source of pterostilbene; some trees produce it in “dragon’s blood,” a red resin with a long history of traditional use.



Pterostilbene Benefits

1. Weight Management

In a study of middle-aged people with high cholesterol, those who were not taking cholesterol medication lost a large, but significant, amount of weight while supplementing with pterostilbene. This result was somewhat surprising, as this study was not designed to measure pterostilbene as a weight loss aid. This result has not yet been investigated in a separate study.


Cell and animal studies also suggest that pterostilbene may help improve insulin sensitivity. Pterostilbene blocks the conversion of sugars into fats and prevents fat cells from multiplying.


Pterostilbene may also change the composition of the gut flora, the colonies of microbes that live in the intestine and help digest food.


2. Mental Health & Neurodegeneration

In mice, pterostilbene reduced anxiety and improved mood. In a study of aged rats, a diet high in pterostilbene increased dopamine and improved cognition. Furthermore, when high levels of pterostilbene were present in the hippocampus of the rats’ brains, their working memory improved.


In another rat study, pterostilbene also promoted the growth of new cells in the hippocampus, the emotion and memory center of the brain. Plus, when stem cells from young rat brains were exposed to pterostilbene, they grew faster.


This same rat study found that pterostilbene was a more powerful antioxidant than its close relative resveratrol. Multiple studies have confirmed that pterostilbene protects against oxidative stress in brain cells.


According to cell research, pterostilbene blocks monoamine oxidase B (MAO-B) and increases available dopamine in the brain. This mechanism is similar to Parkinson’s disease medication like selegiline, rasagiline, and safinamide.


In a cell study, pterostilbene also protected neurons against a specific type of damage associated with Alzheimer’s disease.


3. Blood Sugar

Multiple animal studies suggest that pterostilbene may increase insulin production and thereby decrease blood sugar.


In diabetic mice, pterostilbene protected the pancreas from damage and restored the production of sugar-metabolism enzymes in the liver. These effects are strong enough that some researchers compared pterostilbene to metformin, a diabetes medication.


One safety study on people with high cholesterol found no significant difference in blood sugar between up to 250 mg/day of pterostilbene and the placebo. No human studies have specifically focused on the interaction between pterostilbene and blood glucose. More research is likely to emerge in the coming years.


4. Inflammation

In a rat study, pterostilbene significantly improved the symptoms and cellular markers of severe acute pancreatitis, a disease caused by pancreas inflammation. In people, this disease can cause many complications, including death, and there is no reliable treatment. Pterostilbene may support people suffering from severe acute pancreatitis and improve survival rates.


Some other studies have suggested that pterostilbene is only a weak anti-inflammatory with no useful effect on edema or arthritis. More research is required to understand whether pterostilbene is useful as an anti-inflammatory compound.


5. Liver Function

Pterostilbene protects liver cells from oxidative stress and may even restore some function in damaged liver tissues. In multiple animal studies, pterostilbene prevented scarring (or fibrosis) and inflammatory damage in the liver.


Over-exposure to acetaminophen (also known as paracetamol or Tylenol) is one of the most common causes of liver damage. In mice, pterostilbene prevented liver damage from acetaminophen exposure.


6. Heart Function

Pulmonary heart disease, or cor pulmonale, is a condition wherein the right side of the heart is enlarged, resulting in an abnormal heartbeat, wheezing, discolored skin, and other symptoms.


In one rat study, pterostilbene restored normal antioxidant balance and reduced symptoms of cor pulmonale in the heart. A cell study supported these findings: heart cells and tissues exposed to pterostilbene had an improved antioxidant response in the face of oxidative damage.


Research on pterostilbene and the heart is in its early stages; no studies have investigated its effects on heart disease in people.


7. Vision

The antioxidant properties of pterostilbene may help prevent damage to the eye surface. In one study, pterostilbene protected human corneal cells from oxidative stress; the study’s authors suggested that this compound might help prevent conditions like dry eye.


Researchers are also investigating whether pterostilbene may prevent acquired blindness associated with diabetes.


8. Aging

The most common claim printed on pterostilbene supplement bottles is that it may prevent age-related disorders and thereby extend lifespan, but human trials have yet to investigate its effects on the markers of aging.


In rats, low doses of pterostilbene improved cognitive symptoms of aging. This study was designed to test “diet-achievable” supplementation, which suggests that eating plenty of pterostilbene-rich foods like blueberries may hold off the cognitive decline of old age.


Some researchers have argued that the various mechanisms of pterostilbene may prevent or delay diseases associated with old age like cancer and dementia.


9. Cancer Research

Researchers have studied pterostilbene’s ability to fight breast, esophageal, stomach, colon, pancreatic, prostate, blood, lung, and skin cancer cells. It has become a hot topic of cancer research in recent years.


In rats subjected to UVB radiation (the type of radiation that causes sunburns), a pterostilbene cream on the skin prevented the development of skin cancer. These results were confirmed in cell studies. If these results can be repeated in humans, pterostilbene may be added to sunblock creams as an extra layer of protection.



Where Should We Buy Pterostilbene Powder in Bulk?

With people becoming more and more aware of the benefits of Pterostilbene, the demand for Pterostilbene supplements has increased greatly in the market. This has led to manufacturing companies vying with each other to produce high-quality supplements to grab share in the market. If you are a health supplements manufacturer planning to foray into the Pterostilbene supplements market, you must ensure that you are getting the highest-quality Pterostilbene powder. Sourcing good-quality material is the first step in ensuring the success of any business.


If you are looking for a place to buy Pterostilbene powder in bulk, the one company you can blindly trust for sourcing raw material is Cofttek. The company, owing to its strong research team and dedicated sales department, has established a worldwide presence in only a short amount of time — it has clients and partners around the world. The Pterostilbene produced by the company comes in big batches of 25 kgs and is sourced from highest-quality ingredients, thereby ensuring that the supplements produced from it can be trusted for quality and efficacy. If you want to buy Pterostilbene in bulk, the only place to shop is cofttek.com.





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5. Rodríguez-Bonilla P, et al. Development of a reversed phase high performance liquid chromatography method based on the use of cyclodextrins as mobile phase additives to determine pterostilbene in blueberriesJ Chromatogr B Analyt Technol Biomed Life Sci. (2011)