Hunger for health
The autophagy process is also stimulated by an increase in the level of the hormone glucagon. The rise and fall of glucagon is closely related to insulin levels. When insulin levels rise - glucagon levels fall, it works both ways. When we eat a meal - the insulin level rises, when we fast - it decreases, similarly - it decreases and the level of glucagon increases. Given this state of affairs, it can be concluded that fasting is the most effective known trigger of autophagy.